Benzo-1,3-dioxole-5-methylamine → HCID 118113922, compound
Reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][NH2:11])=[CH:9][C:4]=2[O:3][CH2:2]1.[Br:12][C:13]1[S:17][C:16]2=[N:18][C:19]([C:21](O)=[O:22])=[CH:20][N:15]2[CH:14]=1>>[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][NH:11][C:21]([C:19]3[N:18]=[C:16]4[N:15]([CH:20]=3)[CH:14]=[C:13]([Br:12])[S:17]4)=[O:22])=[CH:9][C:4]=2[O:3][CH2:2]1Participants
3
Procedure
The title compound was prepared by essentially following the same procedures described for Intermediate XLIV, using benzo[d][1,3]dioxol-5-ylmethanamine and 2-bromoimidazo[2,1-b]thiazole-6-carboxylic acid as starting materials.
Sources & evidence
- ORD record
- ord-c7e25e39c68c49e28d47712085bb4607
- Source dataset
- uspto-grants-2016_03
- Patent number
- US09271969B2
Reaction notes
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