2,6-Difluorobenzylamine → HCID 118113916, compound

HRID 918881Notes

Reaction equation

HRID 918881 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[CH2:9][NH2:10].[Br:11][C:12]1[S:16][C:15]2=[N:17][C:18]([C:20](O)=[O:21])=[CH:19][N:14]2[CH:13]=1>>[Br:11][C:12]1[S:16][C:15]2=[N:17][C:18]([C:20]([NH:10][CH2:9][C:3]3[C:2]([F:1])=[CH:7][CH:6]=[CH:5][C:4]=3[F:8])=[O:21])=[CH:19][N:14]2[CH:13]=1

Participants

3

Reactant 2

HCID 1235632,6-DifluorobenzylamineHCID 127446152-Bromoimidazo[2,1-b]thiazole-6-carboxylic acid

Product 1

HCID 118113916HCID 118113916, compound

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate XLIV, using (2,6-difluorophenyl)methanamine and 2-bromoimidazo[2,1-b]thiazole-6-carboxylic acid as starting materials.

Sources & evidence

ORD record
ord-cd286fe06ca5480d9ab6b468dd9cfa31
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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