Phosgene → HCID 67963760, compound

HRID 919044Notes

Reaction equation

HRID 919044 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[NH2:8].[C:9](Cl)(Cl)=[O:10].[C:13]1([C@H:19]([OH:21])[CH3:20])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:13]1([C@H:19]([O:21][C:9](=[O:10])[NH:8][C:3]2[CH:4]=[N:5][CH:6]=[CH:7][C:2]=2[Cl:1])[CH3:20])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 3

HCID 6371PhosgeneHCID 5819323-Amino-4-chloropyridineHCID 6375161-Phenylethanol, (R)-

Product 1

HCID 67963760HCID 67963760, compound

Procedure

Prepared according to the procedure described in Example 1, Step 1, using the following starting materials: 4-chloro-pyridin-3-ylamine, phosgene, and (R)-1-phenyl-ethanol.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-db6453d4e9344818b52ed7665dec8a22
Source dataset
uspto-grants-2016_03
Patent number
US09272990B2

Reaction notes

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