HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[4'-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester → 1-{4'-[2-(1-Hydroxy-4-phenyl-butyl)-thiophen-3-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[4'-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester | HCID 67958039 | — |
| Reactant | 1-(3-Bromo-thiophen-2-yl)-4-phenyl-butan-1-ol | HCID 67963765 | — |
| Product | 1-{4'-[2-(1-Hydroxy-4-phenyl-butyl)-thiophen-3-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester | HCID 67958418 | — |
Reaction Steps
Prepared according to the procedure described in Example 5, Step 2, using the following starting materials: 1-(3-bromo-thiophen-2-yl)-4-phenyl-butan-1-ol and 1-[4′-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09272990B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-e494e9f7049345cab2f52390b7c62af7 |
| Source note | uspto-grants-2016_03 |