2-Bromobenzaldehyde → 1-(2-Bromo-phenyl)-4-phenyl-butan-1-ol

HRID 919059Notes

Reaction equation

[Br:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].[C:10]1([CH2:16][CH2:17][CH2:18][Mg]Br)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[Br:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]([OH:5])[CH2:18][CH2:17][CH2:16][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

Reactant 2

HCID 811292-Bromobenzaldehyde

HCID 178418471HCID 178418471, compound

Product 1

HCID 550951851-(2-Bromo-phenyl)-4-phenyl-butan-1-ol

Procedure

Prepared according to the procedure described in Example 5, Step 1, using the following starting materials: 2-bromo-benzaldehyde and 3-phenyl-propyl magnesium bromide.

Workup

customPrepared

Sources & evidence

ORD record: ord-98f452be8e564d7bbb290016544d16fa
Source dataset: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09272990B2

Reaction notes

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