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1-(4-Bromo-pyridin-3-yl)-4-phenyl-butan-1-ol → 1-{4'-[3-(1-Hydroxy-4-phenyl-butyl)-pyridin-4-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(4-Bromo-pyridin-3-yl)-4-phenyl-butan-1-ol | HCID 67957779 | — |
| 反応物 | 1-[4'-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester | HCID 67958039 | — |
| 生成物 | 1-{4'-[3-(1-Hydroxy-4-phenyl-butyl)-pyridin-4-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester | HCID 67957796 | — |
反応手順
Prepared according to the procedure described in Example 1, Step 2, using the following starting materials: 1-[4′-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 1-(4-bromo-pyridin-3-yl)-4-phenyl-butan-1-ol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09272990B2 |
| 出典データセット | uspto-grants-2016_03 |
| ORD ID | ord-f53c921d69274aa7b649ddf0f4246fa0 |
| 出典メモ | uspto-grants-2016_03 |