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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 919069Generated: October 26, 2026

1-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-phenyl-butan-1-ol → (1-{4'-[5-(1-Hydroxy-4-phenyl-butyl)-1-methyl-1H-pyrazol-4-yl]-biphenyl-4-yl}-cyclopropyl)-acetic acid ethyl ester

https://huagongshe.com/reaction/919069

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-phenyl-butan-1-olHCID 67957995—
Reactant{1-[4'-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropyl}-acetic acid ethyl esterHCID 67963776—
Product(1-{4'-[5-(1-Hydroxy-4-phenyl-butyl)-1-methyl-1H-pyrazol-4-yl]-biphenyl-4-yl}-cyclopropyl)-acetic acid ethyl esterHCID 67959554—

Reaction Steps

Prepared according to the procedure described in Example 5, Step 2, using the following starting materials: 1-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-phenyl-butan-1-ol and {1-[4′-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropyl}-acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09272990B2
Source datasetuspto-grants-2016_03
ORD IDord-eff60807511a40f3b224df6f093bdcfd
Source noteuspto-grants-2016_03