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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 919070Generated: October 26, 2026

1-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-phenyl-butan-1-ol → 1-{4'-[5-(1-Hydroxy-4-phenyl-butyl)-1-methyl-1H-pyrazol-4-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/919070

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-phenyl-butan-1-olHCID 67957995—
Reactant1-[4'-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 67958039—
Product1-{4'-[5-(1-Hydroxy-4-phenyl-butyl)-1-methyl-1H-pyrazol-4-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl esterHCID 67959612—

Reaction Steps

Prepared according to the procedure described in Example 5, Step 2, using the following starting materials: 1-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-phenyl-butan-1-ol and 1-[4′-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09272990B2
Source datasetuspto-grants-2016_03
ORD IDord-5dc8ca2b94c84d1b8f777a4b085f4ebd
Source noteuspto-grants-2016_03