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1-(4-Bromo-thiophen-3-yl)-4-phenyl-butan-1-ol → (1-{4'-[4-(1-Hydroxy-4-phenyl-butyl)-thiophen-3-yl]-biphenyl-4-yl}-cyclopropyl)-acetic acid ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(4-Bromo-thiophen-3-yl)-4-phenyl-butan-1-ol | HCID 67963769 | — |
| 反応物 | {1-[4'-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropyl}-acetic acid ethyl ester | HCID 67963776 | — |
| 生成物 | (1-{4'-[4-(1-Hydroxy-4-phenyl-butyl)-thiophen-3-yl]-biphenyl-4-yl}-cyclopropyl)-acetic acid ethyl ester | HCID 67957739 | — |
反応手順
Prepared according to the procedure described in Example 1, Step 2, using the following starting materials: 1-(4-bromo-thiophen-3-yl)-4-phenyl-butan-1-ol and {1-[4′-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropyl}-acetic acid ethyl ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09272990B2 |
| 出典データセット | uspto-grants-2016_03 |
| ORD ID | ord-c1b80410857e49e98dc88e3867dc5799 |
| 出典メモ | uspto-grants-2016_03 |