3-Bromopyridine-4-carboxaldehyde → 1-(3-Bromo-pyridin-4-yl)-4-phenyl-butan-1-ol

HRID 919078Notes

Reaction equation

HRID 919078 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH:8]=[O:9].[C:10]1([CH2:16][CH2:17][CH2:18][Mg]Br)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>>[Br:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH:8]([OH:9])[CH2:18][CH2:17][CH2:16][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 27629973-Bromopyridine-4-carboxaldehydeHCID 178418471HCID 178418471, compound

Product 1

HCID 679637751-(3-Bromo-pyridin-4-yl)-4-phenyl-butan-1-ol

Procedure

Prepared according to the procedure described in Example 5, Step 1, using the following starting materials: 3-bromo-pyridine-4-carbaldehyde and 3-phenyl-propyl magnesium bromide.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c4fad9c9d7064a0ca9cbf97a236323e3
Source dataset
uspto-grants-2016_03
Patent number
US09272990B2

Reaction notes

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