HRID919084

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID67957971

未命名化合物

结构：CCOC(=O)C1(c2ccc(-c3ccc(B4OC(C)(C)C(C)(C)O4)cc3)cc2)CC1

HCID67958039

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)C1(c2ccc(-c3ccc(-c4cnn(C)c4Nc4cccc(-c5ccccc5)n4)cc3)cc2)CC1

HCID67959565

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure described in Example 5, Step 2, using the following starting materials: (4-bromo-2-methyl-2H-pyrazol-3-yl)-(6-phenyl-pyridin-2-yl)-amine and 1-[4′-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-03dafeba6cc64f70a3cdfef44672d10e
来源数据集: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09272990B2
来源说明: uspto-grants-2016_03

反应 SMILES

Br[C:2]1[CH:6]=[N:5][N:4]([CH3:7])[C:3]=1[NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[N:10]=1.[CH2:21]([O:23][C:24]([C:26]1([C:29]2[CH:34]=[CH:33][C:32]([C:35]3[CH:40]=[CH:39][C:38](B4OC(C)(C)C(C)(C)O4)=[CH:37][CH:36]=3)=[CH:31][CH:30]=2)[CH2:28][CH2:27]1)=[O:25])[CH3:22]>>[CH2:21]([O:23][C:24]([C:26]1([C:29]2[CH:30]=[CH:31][C:32]([C:35]3[CH:36]=[CH:37][C:38]([C:2]4[CH:6]=[N:5][N:4]([CH3:7])[C:3]=4[NH:8][C:9]4[CH:14]=[CH:13][CH:12]=[C:11]([C:15]5[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=5)[N:10]=4)=[CH:39][CH:40]=3)=[CH:33][CH:34]=2)[CH2:28][CH2:27]1)=[O:25])[CH3:22]