HRID919197

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)[C@H]1c2ccc(F)cc2C(F)(F)C[C@]1(O)CC(=O)N(C)CCCc1nc2ccccc2[nH]1

HCID68748561

未命名化合物

结构：[2H]C1([2H])c2cc(F)ccc2C(C(C)C)C(O)(CCN(C)CCCc2nc3ccccc3[nH]2)C1([2H])[2H]

HCID86720677

未命名化合物

PRODUCTS

生成物

结构：CC(C)[C@H]1c2ccc(F)cc2C(F)(F)C[C@]1(O)CCN(C)CCCc1nc2ccccc2[nH]1

HCID68750604

未命名化合物

PROCEDURE

实验过程

35d is prepared from 17d in a manner analogous to that of Example 2, step 2 for 35b.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-cecabc35a4044974973970b90f5520cd
来源数据集: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09273009B2
来源说明: uspto-grants-2016_03

反应 SMILES

[NH:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[CH2:10][CH2:11][CH2:12][N:13]([CH3:34])[C:14](=O)[CH2:15][C@@:16]1([OH:32])[CH2:25][C:24]([F:27])([F:26])[C:23]2[C:18](=[CH:19][CH:20]=[C:21]([F:28])[CH:22]=2)[C@@H:17]1[CH:29]([CH3:31])[CH3:30].N1C2C=CC=CC=2N=C1CCCN(C)CCC1(O)C([2H])([2H])C([2H])([2H])C2C(=CC=C(F)C=2)C1C(C)C>>[NH:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[CH2:10][CH2:11][CH2:12][N:13]([CH3:34])[CH2:14][CH2:15][C@@:16]1([OH:32])[CH2:25][C:24]([F:27])([F:26])[C:23]2[C:18](=[CH:19][CH:20]=[C:21]([F:28])[CH:22]=2)[C@@H:17]1[CH:29]([CH3:31])[CH3:30]