HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-{[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl]methyl}morpholine → 2-Amino-N-(2-methyl-pyridin-4-yl)-5-(5-morpholin-4-ylmethyl-thiophen-3-yl)-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-{[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl]methyl}morpholine | HCID 23438311 | — |
| Reactant | 2-amino-5-bromo-N-(2-methylpyridin-4-yl)nicotinamide | HCID 71060835 | — |
| Product | 2-Amino-N-(2-methyl-pyridin-4-yl)-5-(5-morpholin-4-ylmethyl-thiophen-3-yl)-nicotinamide | HCID 71061230 | — |
Reaction Steps
Reaction of 2-amino-5-bromo-N-(2-methyl-pyridin-4-yl)-nicotinamide with 4-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-thiophen-2-ylmethyl]-morpholine gives the compound “A15”;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273029B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-b7dda7d09ea5479197cfc5de0341ee32 |
| Source note | uspto-grants-2016_03 |