Sodium Carbonate → HCID 71061416, compound

HRID 919231Notes

Reaction equation

HRID 919231 reaction equation
C[O:2][C:3](=[O:26])[C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:11]=[N:12][C:13]([NH2:25])=[C:14]([C:16](=[O:24])[NH:17][C:18]3[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=3)[CH:15]=2)=[CH:6][CH:5]=1.C([O-])([O-])=O.[Na+].[Na+]>CO.O>[NH2:25][C:13]1[N:12]=[CH:11][C:10]([C:7]2[CH:6]=[CH:5][C:4]([C:3]([OH:26])=[O:2])=[CH:9][CH:8]=2)=[CH:15][C:14]=1[C:16](=[O:24])[NH:17][C:18]1[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=1

Participants

5

Reactant 2

HCID 10340Sodium CarbonateHCID 710610754-[6-Amino-5-(pyridin-4-ylcarbamoyl)-pyridin-3-yl]-benzoic acid methyl ester

Product 1

HCID 71061416HCID 71061416, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

190 mg of 4-[6-amino-5-(pyridin-4-ylcarbamoyl)-pyridin-3-yl]-benzoic acid methyl ester are dissolved in 20 ml of MeOH. 175 mg Na2CO3 in 6 ml of water are added.

Sources & evidence

ORD record
ord-f526b17bae804191981780c9fe9b597f
Source dataset
uspto-grants-2016_03
Patent number
US09273029B2

Reaction notes

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