HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → 2-Amino-5-(3-hydroxy-phenyl)-N-pyridin-4-yl-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol | HCID 2734623 | — |
| Reactant | 2-amino-5-bromo-N-(pyridin-4-yl)nicotinamide | HCID 62155416 | — |
| Product | 2-Amino-5-(3-hydroxy-phenyl)-N-pyridin-4-yl-nicotinamide | HCID 71062778 | — |
Reaction Steps
Reaction of 2-amino-5-bromo-N-pyridin-4-yl-nicotinamide with 3-hydroxyphenyl-boronic acid pinacol ester gives “A70”; method 1: HPLC/MS: 1.12 min, [M+H]=307.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273029B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-01c6068832184c29ad85c5176da1f477 |
| Source note | uspto-grants-2016_03 |