HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate → 2-[6-Amino-5-(pyridin-4-ylcarbamoyl)-pyridin-3-yl]-benzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate | HCID 2773962 | — |
| Reactant | 2-amino-5-bromo-N-(pyridin-4-yl)nicotinamide | HCID 62155416 | — |
| Product | 2-[6-Amino-5-(pyridin-4-ylcarbamoyl)-pyridin-3-yl]-benzoic acid ethyl ester | HCID 71060771 | — |
Reaction Steps
Reaction of 2-amino-5-bromo-N-pyridin-4-yl-nicotinamide with ethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate gives “A70”; method 1: HPLC/MS: 1.37 min, [M+H]=363;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273029B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-a6b54524825443aaa4858ab22f605ddb |
| Source note | uspto-grants-2016_03 |