HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boronic acid, B-(3-(aminomethyl)phenyl)-, hydrochloride (1:1) → 2-Amino-5-(3-aminomethyl-phenyl)-N-pyridin-4-yl-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boronic acid, B-(3-(aminomethyl)phenyl)-, hydrochloride (1:1) | HCID 16427085 | — |
| Reactant | 2-amino-5-bromo-N-(pyridin-4-yl)nicotinamide | HCID 62155416 | — |
| Product | 2-Amino-5-(3-aminomethyl-phenyl)-N-pyridin-4-yl-nicotinamide | HCID 71062601 | — |
Reaction Steps
Reaction of 2-amino-5-bromo-N-pyridin-4-yl-nicotinamide with 3-aminomethyl-phenylboronic acid hydrochloride gives “A76”; method 1: HPLC/MS: 0.94 min, [M+H]=320;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273029B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-7eae835e32d44cb1ae30075606e373ed |
| Source note | uspto-grants-2016_03 |