N-Methyl-1-(1-methyl-1H-imidazol-5-yl)methanamine → HCID 71063020, compound

HRID 919272Notes

Reaction equation

HRID 919272 reaction equation
[NH2:1][C:2]1[N:7]=[CH:6][C:5]([C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=O)=[CH:10][CH:9]=2)=[CH:4][C:3]=1[C:17](=[O:25])[NH:18][C:19]1[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=1.[CH3:26][NH:27][CH2:28][C:29]1[N:30]([CH3:34])[CH:31]=[N:32][CH:33]=1>>[NH2:1][C:2]1[N:7]=[CH:6][C:5]([C:8]2[CH:16]=[CH:15][C:11]([C:12](=[O:14])[N:27]([CH3:26])[CH2:28][C:29]3[N:30]([CH3:34])[CH:31]=[N:32][CH:33]=3)=[CH:10][CH:9]=2)=[CH:4][C:3]=1[C:17]([NH:18][C:19]1[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=1)=[O:25]

Participants

3

Reactant 2

HCID 7164555N-Methyl-1-(1-methyl-1H-imidazol-5-yl)methanamineHCID 71061416HCID 71061416, compound

Product 1

HCID 71063020HCID 71063020, compound

Procedure

Reaction of 4-[6-amino-5-(pyridin-4-ylcarbamoyl)-pyridin-3-yl]-benzoic acid with methyl-(3-methyl-3H-imidazol-4-ylmethyl)-amine gives “A95”; method 1: HPLC/MS: 1.07 min, [M+H]=442;

Workup

  1. customgives “A95”
  2. custom1.07 min, [M+H]=442

Sources & evidence

ORD record
ord-5ea5b001bd9f4882a935484551c893c6
Source dataset
uspto-grants-2016_03
Patent number
US09273029B2

Reaction notes

Loading…