2,6-Benzothiazolediamine → HCID 86664245, compound

HRID 919389Notes

Reaction equation

HRID 919389 reaction equation
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([NH2:11])[CH:8]=[CH:7][C:5]=2[N:6]=1.[CH3:12][N:13]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[C:14]1[C:21]([OH:23])=O>>[CH3:12][N:13]1[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=[C:14]1[C:21]([NH:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([NH:11][C:21]([C:14]3[N:13]([CH3:12])[CH:17]=[C:16]([N+:18]([O-:20])=[O:19])[CH:15]=3)=[O:23])[CH:8]=[CH:7][C:5]=2[N:6]=1)=[O:23]

Participants

3

Reactant 2

HCID 215042,6-BenzothiazolediamineHCID 27369151-Methyl-4-nitropyrrole-2-carboxylic acid

Product 1

HCID 86664245HCID 86664245, compound

Procedure

The compound 8b was prepared according to the above described method using compound 7 (165 mg, 1 mmol) and 1-methyl-4-nitro-1H-pyrrole-2-carboxylic acid (340 mg, 2 mmol). Yield 290 mg, 60%; 1H NMR (DMSO-d6) δ 10.9 (bs, 1H, —NH), 8.54 (s, 1H), 7.95 (s, 2H), 7.74-7.71 (m, 2H), 7.50 (s, 2H), 3.96 (s, 6H); ESIMS: m/z 470 (M+H)+.

Sources & evidence

ORD record
ord-7bd5da26514c477bb1e39558b738b28f
Source dataset
uspto-grants-2016_03
Patent number
US09273039B2

Reaction notes

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