Water → HCID 89816112, compound

Participants

Reaction Steps

To a solution of the product of step 1 (1.4 gm, 4.15 mmoles) in a mixture of methanol (10 ml), THF (30 ml) and H2O (10 ml), lithium hydroxide (0.35 gm, 8.30 mmoles) was added and the reaction mixture was stirred at ambient temperature for 4 hours. The solvents were evaporated under reduced pressure. The residue was dissolved in water and acidified with 1N HCl. The solid separated which was filtered, washed with water & dried over P2O5 under vacuum to give 1.25 g of title product as pale brown solid.

Provenance & Evidence