HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 4-((tert-Butyldimethylsilyl)oxy)benzene-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 4-(Tert-butyldimethylsilyl)oxy-2-nitroaniline | HCID 12042299 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-((tert-Butyldimethylsilyl)oxy)benzene-1,2-diamine | HCID 67278658 | — |
Reaction Steps
The mixture of 4-(tert-butyldimethylsilyloxy)-2-nitrobenzenamine (0.5 g, 1.9 mmol), Fe powder (1.1 g, 19 mmol) and acetic acid (1.0 mL, 18 mmol) in EtOH (10 mL) was stirred at reflux for 4 hrs. The mixture was filtered through celite pad and the filtrate was concentrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273046B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-64301a4e86764faaa072ab461b72ee38 |
| Source note | uspto-grants-2016_03 |