Propanal → 2-Chloro-4-{2-[4-(3-{[ethyl-(1-propyl-piperidin-4-yl)-amino]-methyl}-phenyl)-pyrimidin-2-ylamino]-ethyl}-phenol

HRID 92013Notes

Reaction equation

HRID 92013 reaction equation
[CH:34]([CH2:35][CH3:36])=[O:37].[Cl:1][c:2]1[c:3]([OH:33])[cH:4][cH:5][c:6]([CH2:8][CH2:9][NH:10][c:11]2[n:12][cH:13][cH:14][c:15](-[c:17]3[cH:18][c:19]([CH2:23][N:24]([CH:25]4[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]4)[CH2:31][CH3:32])[cH:20][cH:21][cH:22]3)[n:16]2)[cH:7]1>>[Cl:1][c:2]1[c:3]([OH:33])[cH:4][cH:5][c:6]([CH2:8][CH2:9][NH:10][c:11]2[n:12][cH:13][cH:14][c:15](-[c:17]3[cH:18][c:19]([CH2:23][N:24]([CH:25]4[CH2:26][CH2:27][N:28]([CH2:34][CH2:35][CH3:36])[CH2:29][CH2:30]4)[CH2:31][CH3:32])[cH:20][cH:21][cH:22]3)[n:16]2)[cH:7]1

Participants

3

Reactant 2

HCID 527PropanalHCID 586034392-Chloro-4-[2-(4-{3-[(ethyl-piperidin-4-yl-amino)-methyl]-phenyl}-pyrimidin-2-ylamino)-ethyl]-phenol

Product 1

HCID 586037692-Chloro-4-{2-[4-(3-{[ethyl-(1-propyl-piperidin-4-yl)-amino]-methyl}-phenyl)-pyrimidin-2-ylamino]-ethyl}-phenol

Sources & evidence

ORD record
ord-51c63c7bb2dc4df8bf4bd9694d830759
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…