HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 89525943, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 117638131 | HCID 117638131 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 89525943 | HCID 89525943 | — |
Reaction Steps
Added 35-4 (120 mg, 0.153 mmol) to DCM (610 μl) and TFA (306 μl). After 90 min, diluted with 1 mL MeOH, filtered through Celite, washed with MeOH. Concentrated filtrate in vacuo and dissolved in 2 mL DMSO. Purified by reverse-phase HPLC (C18 column, 2-60% 0.1% TFA/CH3CN:0.1% TFA/H2O) to give 35-5 as a white solid
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273040B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-295f1705754c4b1a8b9932a33d399a90 |
| Source note | uspto-grants-2016_03 |