4-Fluorobenzaldehyde → 4-(4-Chloro-3-(trifluoromethyl)phenoxy)benzaldehyde

HRID 920288Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[C:9]([F:12])([F:11])[F:10].F[C:14]1[CH:21]=[CH:20][C:17]([CH:18]=[O:19])=[CH:16][CH:15]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:14]2[CH:21]=[CH:20][C:17]([CH:18]=[O:19])=[CH:16][CH:15]=2)=[CH:4][C:3]=1[C:9]([F:10])([F:11])[F:12]

Participants

Reactant 2

HCID 680234-Fluorobenzaldehyde

HCID 805204-Chloro-3-(trifluoromethyl)phenol

Product 1

HCID 866661874-(4-Chloro-3-(trifluoromethyl)phenoxy)benzaldehyde

Procedure

The title compound was prepared by a procedure similar to that described for D4 starting from 4-chloro-3-trifluoromethyl-phenol and 4-fluoro-benzaldehyde.

Sources & evidence

ORD record: ord-df8001aa43ce4d498d2439417f5caae9
Source dataset: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09273054B2

Reaction notes

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