3-Fluoro-4-hydroxybenzaldehyde → 3-Fluoro-4-((6-(trifluoromethyl)pyridin-2-yl)oxy)benzaldehyde

HRID 920303Notes

Reaction equation

HRID 920303 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[OH:10])[CH:5]=[O:6].Cl[C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([C:18]([F:21])([F:20])[F:19])[N:13]=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:10][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([C:18]([F:21])([F:20])[F:19])[N:13]=1)[CH:5]=[O:6]

Participants

3

Reactant 2

HCID 5872503-Fluoro-4-hydroxybenzaldehydeHCID 6023342-Chloro-6-(trifluoromethyl)pyridine

Product 1

HCID 866662133-Fluoro-4-((6-(trifluoromethyl)pyridin-2-yl)oxy)benzaldehyde

Procedure

The title compound was prepared by a procedure similar to that described for D4 starting from 3-fluoro-4-hydroxybenzaldehyde and 2-chloro-6-(trifluoromethyl)pyridine.

Sources & evidence

ORD record
ord-dae0665239ab4c01ba8712c25399d96c
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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