2-Methyl-5-hydroxypyridine → HCID 86676375, compound

HRID 920321Notes

Reaction equation

HRID 920321 reaction equation
[CH3:1][C:2]1[N:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.F[C:10]1[CH:17]=[CH:16][C:15]([CH:18]=[O:19])=[CH:14][C:11]=1[C:12]#[N:13]>>[CH:18]([C:15]1[CH:16]=[CH:17][C:10]([O:8][C:5]2[CH:6]=[N:7][C:2]([CH3:1])=[CH:3][CH:4]=2)=[C:11]([CH:14]=1)[C:12]#[N:13])=[O:19]

Participants

3

Reactant 2

HCID 142752-Methyl-5-hydroxypyridineHCID 27695822-Fluoro-5-formylbenzonitrile

Product 1

HCID 86676375HCID 86676375, compound

Procedure

The title compound was prepared by a procedure similar to that described for D4 starting from 6-methyl-3-pyridinol and 2-fluoro-5-formylbenzonitrile.

Sources & evidence

ORD record
ord-4eb686e52631414095daf0219656be20
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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