3,4-Difluorobenzaldehyde → 3-Fluoro-5-(2-fluoro-4-formyl-phenoxy)-benzonitrile

HRID 920343Notes

Reaction equation

HRID 920343 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1F)[CH:5]=[O:6].[F:11][C:12]1[CH:13]=[C:14]([CH:17]=[C:18]([OH:20])[CH:19]=1)[C:15]#[N:16]>>[F:11][C:12]1[CH:13]=[C:14]([CH:17]=[C:18]([O:20][C:9]2[CH:8]=[CH:7][C:4]([CH:5]=[O:6])=[CH:3][C:2]=2[F:1])[CH:19]=1)[C:15]#[N:16]

Participants

3

Reactant 2

HCID 5880883,4-DifluorobenzaldehydeHCID 219499203-Fluoro-5-hydroxybenzonitrile

Product 1

HCID 866763853-Fluoro-5-(2-fluoro-4-formyl-phenoxy)-benzonitrile

Procedure

The title compound was prepared by a procedure similar to that described for D4 starting from 3,4-difluorobenzaldehyde and 3-fluoro-5-hydroxybenzonitrile.

Sources & evidence

ORD record
ord-9b6d9a3870234a98a7051b78dbb81608
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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