4-Fluorobenzylic alcohol → HCID 71236568, compound

HRID 920369Notes

Reaction equation

HRID 920369 reaction equation
Cl[C:2]1[CH:12]=[C:6]2[N:7]([CH3:11])[CH2:8][CH2:9][CH2:10][N:5]2[C:4](=[O:13])[N:3]=1.[F:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][OH:22])=[CH:17][CH:16]=1>>[F:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][O:22][C:2]2[CH:12]=[C:6]3[N:7]([CH3:11])[CH2:8][CH2:9][CH2:10][N:5]3[C:4](=[O:13])[N:3]=2)=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 680224-Fluorobenzylic alcoholHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236568HCID 71236568, compound

Procedure

The title compound was prepared by a procedure similar to that described for E1 starting from 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one and (4-fluorophenyl)methanol.

Sources & evidence

ORD record
ord-aaf85d39aca447d5aca015bb434dd5bd
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

Loading…