HCID 43554866, compound → HCID 71236716, compound

HRID 920372Notes

Reaction equation

HRID 920372 reaction equation
Cl[C:2]1[CH:12]=[C:6]2[N:7]([CH3:11])[CH2:8][CH2:9][CH2:10][N:5]2[C:4](=[O:13])[N:3]=1.[F:14][C:15]1[CH:16]=[C:17]([CH:27]=[CH:28][C:29]=1[F:30])[O:18][C:19]1[CH:24]=[CH:23][C:22]([CH2:25][OH:26])=[CH:21][CH:20]=1>>[F:14][C:15]1[CH:16]=[C:17]([CH:27]=[CH:28][C:29]=1[F:30])[O:18][C:19]1[CH:24]=[CH:23][C:22]([CH2:25][O:26][C:2]2[CH:12]=[C:6]3[N:7]([CH3:11])[CH2:8][CH2:9][CH2:10][N:5]3[C:4](=[O:13])[N:3]=2)=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 43554866HCID 43554866, compoundHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236716HCID 71236716, compound

Procedure

The title compound was prepared by a procedure similar to that described for E1 starting from 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one and (4-(3,4-difluorophenoxy)phenyl)methanol.

Sources & evidence

ORD record
ord-db1d564d7c2a481da910e699412a14e3
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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