4-(Trifluoromethyl)benzenemethanol → HCID 71236861, compound

HRID 920379Notes

Reaction equation

HRID 920379 reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:8]=[CH:7][C:6]([CH2:9][OH:10])=[CH:5][CH:4]=1.Cl[C:14]1[CH:24]=[C:18]2[N:19]([CH3:23])[CH2:20][CH2:21][CH2:22][N:17]2[C:16](=[O:25])[N:15]=1>>[CH3:23][N:19]1[CH2:20][CH2:21][CH2:22][N:17]2[C:16](=[O:25])[N:15]=[C:14]([O:10][CH2:9][C:6]3[CH:5]=[CH:4][C:3]([C:2]([F:11])([F:12])[F:1])=[CH:8][CH:7]=3)[CH:24]=[C:18]12

Participants

3

Reactant 2

HCID 676844-(Trifluoromethyl)benzenemethanolHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236861HCID 71236861, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E2 starting from (4-(trifluoromethyl)phenyl)methanol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-c3fa7c602eaf43d784940a6b2f622ab5
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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