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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 920381Generated: October 30, 2026

(3-Fluoro-4-(3-fluorophenoxy)phenyl)methanol → 8-((3-fluoro-4-(3-fluorophenoxy)benzyl)oxy)-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one

https://huagongshe.com/reaction/920381

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Fluoro-4-(3-fluorophenoxy)phenyl)methanolHCID 28946122—
Reactant8-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-oneHCID 71743471—
Product8-((3-fluoro-4-(3-fluorophenoxy)benzyl)oxy)-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-oneHCID 71236593—

Reaction Steps

The title compound or its salt was prepared by a procedure similar to that described for E2 starting from (3-fluoro-4-(3-fluorophenoxy)phenyl)methanol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09273054B2
Source datasetuspto-grants-2016_03
ORD IDord-9659bc9852e74ba98e96ab586e3e8372
Source noteuspto-grants-2016_03