(4-Phenoxyphenyl)methanol → HCID 71236645, compound
Reaction equation
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([CH2:14][OH:15])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[C:17]1[CH:27]=[C:21]2[N:22]([CH3:26])[CH2:23][CH2:24][CH2:25][N:20]2[C:19](=[O:28])[N:18]=1>>[CH3:26][N:22]1[CH2:23][CH2:24][CH2:25][N:20]2[C:19](=[O:28])[N:18]=[C:17]([O:15][CH2:14][C:11]3[CH:10]=[CH:9][C:8]([O:1][C:2]4[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=4)=[CH:13][CH:12]=3)[CH:27]=[C:21]12Participants
3
Procedure
The title compound or its salt was prepared by a procedure similar to that described for E2 starting from (4-phenoxyphenyl)methanol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.
Sources & evidence
- ORD record
- ord-a252c919efbb4923ba57353ce70cf8dd
- Source dataset
- uspto-grants-2016_03
- Patent number
- US09273054B2
Reaction notes
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