3-(Hydroxymethyl)benzonitrile → HCID 71236667, compound

HRID 920383Notes

Reaction equation

HRID 920383 reaction equation
[OH:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[C:6]#[N:7].Cl[C:12]1[CH:22]=[C:16]2[N:17]([CH3:21])[CH2:18][CH2:19][CH2:20][N:15]2[C:14](=[O:23])[N:13]=1>>[CH3:21][N:17]1[CH2:18][CH2:19][CH2:20][N:15]2[C:14](=[O:23])[N:13]=[C:12]([O:1][CH2:2][C:3]3[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=3)[C:6]#[N:7])[CH:22]=[C:16]12

Participants

3

Reactant 2

HCID 27346773-(Hydroxymethyl)benzonitrileHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236667HCID 71236667, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E2 starting from 3-(hydroxymethyl)benzonitrile and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-57554dd81607406a9618b14c497defd5
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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