HCID 71236744, compound → HCID 71236612, compound

HRID 920385Notes

Reaction equation

HRID 920385 reaction equation
[OH:1][CH2:2][C:3]1[CH:4]=[CH:5][C:6]([O:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][CH:13]=2)=[C:7]([CH:10]=1)[C:8]#[N:9].Cl[C:23]1[CH:33]=[C:27]2[N:28]([CH3:32])[CH2:29][CH2:30][CH2:31][N:26]2[C:25](=[O:34])[N:24]=1>>[CH3:32][N:28]1[CH2:29][CH2:30][CH2:31][N:26]2[C:25](=[O:34])[N:24]=[C:23]([O:1][CH2:2][C:3]3[CH:4]=[CH:5][C:6]([O:11][C:12]4[CH:17]=[CH:16][C:15]([C:18]([F:19])([F:20])[F:21])=[CH:14][CH:13]=4)=[C:7]([CH:10]=3)[C:8]#[N:9])[CH:33]=[C:27]12

Participants

3

Reactant 2

HCID 71236744HCID 71236744, compoundHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236612HCID 71236612, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E2 starting from 5-(hydroxymethyl)-2-(4-(trifluoromethyl)phenoxy)benzonitrile and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-1c331d3b43d04de0b060dd98f7ccafb7
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

Loading…