HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluoro-5-(hydroxymethyl)benzonitrile → 3-fluoro-5-(((1-methyl-6-oxo-2,3,4,6-tetrahydro-1H-pyrimido[1,6-a]pyrimidin-8-yl)oxy)methyl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluoro-5-(hydroxymethyl)benzonitrile | HCID 68662252 | — |
| Reactant | 8-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one | HCID 71743471 | — |
| Product | 3-fluoro-5-(((1-methyl-6-oxo-2,3,4,6-tetrahydro-1H-pyrimido[1,6-a]pyrimidin-8-yl)oxy)methyl)benzonitrile | HCID 71236747 | — |
Reaction Steps
The title compound or its salt was prepared by a procedure similar to that described for E2 starting from 3-fluoro-5-(hydroxymethyl)benzonitrile and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273054B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-5f92cf4c2c024640aa0225bd14c4ed19 |
| Source note | uspto-grants-2016_03 |