2-(4-(Trifluoromethyl)phenyl)ethan-1-ol → HCID 71236592, compound

HRID 920395Notes

Reaction equation

HRID 920395 reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][OH:11])=[CH:5][CH:4]=1.Cl[C:15]1[CH:25]=[C:19]2[N:20]([CH3:24])[CH2:21][CH2:22][CH2:23][N:18]2[C:17](=[O:26])[N:16]=1>>[CH3:24][N:20]1[CH2:21][CH2:22][CH2:23][N:18]2[C:17](=[O:26])[N:16]=[C:15]([O:11][CH2:10][CH2:9][C:6]3[CH:5]=[CH:4][C:3]([C:2]([F:12])([F:13])[F:1])=[CH:8][CH:7]=3)[CH:25]=[C:19]12

Participants

3

Reactant 2

HCID 112755102-(4-(Trifluoromethyl)phenyl)ethan-1-olHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236592HCID 71236592, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E11 starting from 2-(4-(trifluoromethyl)phenyl)ethanol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-ac66ac16fa654e1db351e1b624c9b5ab
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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