3,4,5-Trifluorobenzeneethanol → HCID 71236651, compound

HRID 920398Notes

Reaction equation

HRID 920398 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH2:10][CH2:11][OH:12])[CH:5]=[C:6]([F:9])[C:7]=1[F:8].Cl[C:14]1[CH:24]=[C:18]2[N:19]([CH3:23])[CH2:20][CH2:21][CH2:22][N:17]2[C:16](=[O:25])[N:15]=1>>[CH3:23][N:19]1[CH2:20][CH2:21][CH2:22][N:17]2[C:16](=[O:25])[N:15]=[C:14]([O:12][CH2:11][CH2:10][C:4]3[CH:3]=[C:2]([F:1])[C:7]([F:8])=[C:6]([F:9])[CH:5]=3)[CH:24]=[C:18]12

Participants

3

Reactant 2

HCID 177508383,4,5-TrifluorobenzeneethanolHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236651HCID 71236651, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E11 starting from 2-(3,4,5-trifluorophenyl)ethanol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-89f9f352bf754de9b7a335f195adb6c4
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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