2-(3-fluoro-4-methylphenyl)ethanol → HCID 71236620, compound
Reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH2:9][CH2:10][OH:11])[CH:5]=[CH:6][C:7]=1[CH3:8].Cl[C:13]1[CH:23]=[C:17]2[N:18]([CH3:22])[CH2:19][CH2:20][CH2:21][N:16]2[C:15](=[O:24])[N:14]=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][C:7]=1[CH3:8])[CH2:9][CH2:10][O:11][C:13]1[CH:23]=[C:17]2[N:18]([CH3:22])[CH2:19][CH2:20][CH2:21][N:16]2[C:15](=[O:24])[N:14]=1Participants
3
Procedure
The title compound or its salt was prepared by a procedure similar to that described for E11 starting from of 2-(3-fluoro-4-methylphenyl)ethanol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.
Sources & evidence
- ORD record
- ord-a0c727d813994271af94edda4499e29b
- Source dataset
- uspto-grants-2016_03
- Patent number
- US09273054B2
Reaction notes
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