HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluoro-4-(trifluoromethyl)benzyl alcohol → 8-((3-fluoro-4-(trifluoromethyl)benzyl)oxy)-1-isopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluoro-4-(trifluoromethyl)benzyl alcohol | HCID 2737562 | — |
| Reactant | 8-Chloro-1-isopropyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one | HCID 71743470 | — |
| Product | 8-((3-fluoro-4-(trifluoromethyl)benzyl)oxy)-1-isopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one | HCID 71236724 | — |
Reaction Steps
The title compound or its salt was prepared by a procedure similar to that described for E2 starting from (3-fluoro-4-(trifluoromethyl)phenyl)methanol and 8-chloro-1-isopropyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273054B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-f9265ca2ec2648e894ad57b2cd66ef96 |
| Source note | uspto-grants-2016_03 |