4-(2-Hydroxyethyl)benzonitrile → HCID 71236737, compound

HRID 920406Notes

Reaction equation

HRID 920406 reaction equation
[OH:1][CH2:2][CH2:3][C:4]1[CH:11]=[CH:10][C:7]([C:8]#[N:9])=[CH:6][CH:5]=1.Cl[C:13]1[CH:23]=[C:17]2[N:18]([CH3:22])[CH2:19][CH2:20][CH2:21][N:16]2[C:15](=[O:24])[N:14]=1>>[CH3:22][N:18]1[CH2:19][CH2:20][CH2:21][N:16]2[C:15](=[O:24])[N:14]=[C:13]([O:1][CH2:2][CH2:3][C:4]3[CH:11]=[CH:10][C:7]([C:8]#[N:9])=[CH:6][CH:5]=3)[CH:23]=[C:17]12

Participants

3

Reactant 2

HCID 28008154-(2-Hydroxyethyl)benzonitrileHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236737HCID 71236737, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E11 starting from of 4-(2-hydroxyethyl)benzonitrile and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-c0802d1b09f448c8a8c975ad83789250
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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