2-(4-(4-Chloro-3-(trifluoromethyl)phenoxy)phenyl)ethanol → HCID 71236600, compound

HRID 920407Notes

Reaction equation

HRID 920407 reaction equation
[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][OH:15])=[CH:9][CH:8]=2)=[CH:4][C:3]=1[C:18]([F:21])([F:20])[F:19].Cl[C:23]1[CH:33]=[C:27]2[N:28]([CH3:32])[CH2:29][CH2:30][CH2:31][N:26]2[C:25](=[O:34])[N:24]=1>>[Cl:1][C:2]1[CH:17]=[CH:16][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([CH2:13][CH2:14][O:15][C:23]3[CH:33]=[C:27]4[N:28]([CH3:32])[CH2:29][CH2:30][CH2:31][N:26]4[C:25](=[O:34])[N:24]=3)=[CH:9][CH:8]=2)=[CH:4][C:3]=1[C:18]([F:19])([F:20])[F:21]

Participants

3

Reactant 2

HCID 668255292-(4-(4-Chloro-3-(trifluoromethyl)phenoxy)phenyl)ethanolHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236600HCID 71236600, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E2 starting from 2-(4-(4-chloro-3-(trifluoromethyl)phenoxy)phenyl) ethanol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-dadde8ed063446af9cd23e1a5079cdcc
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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