HCID 66825453, compound → HCID 71236851, compound

HRID 920408Notes

Reaction equation

HRID 920408 reaction equation
[OH:1][CH2:2][C:3]1[CH:4]=[CH:5][C:6]([O:11][C:12]2[CH:13]=[N:14][C:15]([CH3:18])=[CH:16][CH:17]=2)=[C:7]([CH:10]=1)[C:8]#[N:9].Cl[C:20]1[CH:30]=[C:24]2[N:25]([CH3:29])[CH2:26][CH2:27][CH2:28][N:23]2[C:22](=[O:31])[N:21]=1>>[CH3:29][N:25]1[CH2:26][CH2:27][CH2:28][N:23]2[C:22](=[O:31])[N:21]=[C:20]([O:1][CH2:2][C:3]3[CH:4]=[CH:5][C:6]([O:11][C:12]4[CH:13]=[N:14][C:15]([CH3:18])=[CH:16][CH:17]=4)=[C:7]([CH:10]=3)[C:8]#[N:9])[CH:30]=[C:24]12

Participants

3

Reactant 2

HCID 66825453HCID 66825453, compoundHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236851HCID 71236851, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E2 starting from 5-(hydroxymethyl)-2-((6-methylpyridin-3-yl)oxy)benzonitrile and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-2a872eb0940645358e16d8d82b280ab5
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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