2,4-Difluorobenzylamine → HCID 71236649, compound

HRID 920414Notes

Reaction equation

HRID 920414 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[CH2:9][NH2:10].Cl[C:12]1[CH:22]=[C:16]2[N:17]([CH3:21])[CH2:18][CH2:19][CH2:20][N:15]2[C:14](=[O:23])[N:13]=1>>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[CH2:9][NH:10][C:12]1[CH:22]=[C:16]2[N:17]([CH3:21])[CH2:18][CH2:19][CH2:20][N:15]2[C:14](=[O:23])[N:13]=1

Participants

3

Reactant 2

HCID 27332442,4-DifluorobenzylamineHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236649HCID 71236649, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E59 starting from (2,4-difluorophenyl)methanamine and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-42b672ad7e324a6cad8b0b8cdeebdc90
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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