p-Fluorotoluene-alpha-thiol → HCID 71236559, compound

HRID 920416Notes

Reaction equation

HRID 920416 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][SH:9])=[CH:4][CH:3]=1.Cl[C:11]1[CH:21]=[C:15]2[N:16]([CH3:20])[CH2:17][CH2:18][CH2:19][N:14]2[C:13](=[O:22])[N:12]=1>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][S:9][C:11]2[CH:21]=[C:15]3[N:16]([CH3:20])[CH2:17][CH2:18][CH2:19][N:14]3[C:13](=[O:22])[N:12]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 85171p-Fluorotoluene-alpha-thiolHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236559HCID 71236559, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E62 starting from (4-fluorophenyl)methanethiol and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-6ba38e23addb4f4f8dc2ae08a828bf89
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

Loading…