3-Fluorobenzylamine → HCID 71236674, compound

HRID 920419Notes

Reaction equation

HRID 920419 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH2:8][NH2:9])[CH:5]=[CH:6][CH:7]=1.Cl[C:11]1[CH:21]=[C:15]2[N:16]([CH3:20])[CH2:17][CH2:18][CH2:19][N:14]2[C:13](=[O:22])[N:12]=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][CH:7]=1)[CH2:8][NH:9][C:11]1[CH:21]=[C:15]2[N:16]([CH3:20])[CH2:17][CH2:18][CH2:19][N:14]2[C:13](=[O:22])[N:12]=1

Participants

3

Reactant 2

HCID 668533-FluorobenzylamineHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236674HCID 71236674, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E59 starting from (3-fluorophenyl)methanamine and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-4f0792b80bb74f44bf48cd7dd3f00f72
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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