HCID 66825616, compound → HCID 71236606, compound

HRID 920424Notes

Reaction equation

HRID 920424 reaction equation
[OH:1][CH2:2][C:3]1[CH:4]=[CH:5][C:6]([O:11][C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[C:7]([CH:10]=1)[C:8]#[N:9].Cl[C:19]1[CH:29]=[C:23]2[N:24]([CH3:28])[CH2:25][CH2:26][CH2:27][N:22]2[C:21](=[O:30])[N:20]=1>>[CH3:28][N:24]1[CH2:25][CH2:26][CH2:27][N:22]2[C:21](=[O:30])[N:20]=[C:19]([O:1][CH2:2][C:3]3[CH:4]=[CH:5][C:6]([O:11][C:12]4[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=4)=[C:7]([CH:10]=3)[C:8]#[N:9])[CH:29]=[C:23]12

Participants

3

Reactant 2

HCID 66825616HCID 66825616, compoundHCID 717434718-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one

Product 1

HCID 71236606HCID 71236606, compound

Procedure

The title compound or its salt was prepared by a procedure similar to that described for E2 starting from 5-(hydroxymethyl)-2-(pyridin-3-yloxy)benzonitrile and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.

Sources & evidence

ORD record
ord-41e18731ac1b46a291a07382f8733a71
Source dataset
uspto-grants-2016_03
Patent number
US09273054B2

Reaction notes

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