HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Chloro-4-fluorophenoxy)-5-(hydroxymethyl)benzonitrile → 2-(3-chloro-4-fluorophenoxy)-5-(((1-methyl-6-oxo-2,3,4,6-tetrahydro-1H-pyrimido[1,6-a]pyrimidin-8-yl)oxy)methyl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Chloro-4-fluorophenoxy)-5-(hydroxymethyl)benzonitrile | HCID 71236832 | — |
| Reactant | 8-Chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-A]pyrimidin-6(2H)-one | HCID 71743471 | — |
| Product | 2-(3-chloro-4-fluorophenoxy)-5-(((1-methyl-6-oxo-2,3,4,6-tetrahydro-1H-pyrimido[1,6-a]pyrimidin-8-yl)oxy)methyl)benzonitrile | HCID 71236762 | — |
Reaction Steps
The title compound or its salt was prepared by a procedure similar to that described for E2 starting from 2-(3-chloro-4-fluorophenoxy)-5-(hydroxymethyl)benzonitrile and 8-chloro-1-methyl-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273054B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-5844b5e710ae4553a765b6e0af593f05 |
| Source note | uspto-grants-2016_03 |