HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 63077406, compound → 8-((3,5-difluoro-4-(4-fluorophenoxy)benzyl)oxy)-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 63077406 | HCID 63077406 | — |
| Reactant | Tert-butyl 8-chloro-6-oxo-2,3,4,6-tetrahydro-1H-pyrimido[1,6-A]pyrimidine-1-carboxylate | HCID 71743562 | — |
| Product | 8-((3,5-difluoro-4-(4-fluorophenoxy)benzyl)oxy)-3,4-dihydro-1H-pyrimido[1,6-a]pyrimidin-6(2H)-one | HCID 71236652 | — |
Reaction Steps
The title compound or its salt was prepared by a procedure similar to that described for E111 starting from (3,5-difluoro-4-(4-fluorophenoxyl)phenyl)methanol and tert-butyl 8-chloro-6-oxo-2,3,4,6-tetrahydro-1H-pyrimido[1,6-a]pyrimidine-1-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09273054B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-568fac1ae8414b61b3d232d30ddb3b85 |
| Source note | uspto-grants-2016_03 |