6-(Trifluoromethyl)nicotinoyl chloride → N-[6-(4-Chlorobenzyl)-1-(2,4-dichlorobenzenesulfonyl)-8-isopropyl-4,7-dioxooctahydropyrazino[1,2-a]pyrimidin-3-yl]-6-trifluoromethylnicotinamide
Reaction equation
[F:1][C:2]([c:3]1[n:4][cH:5][c:6]([C:7](=[O:8])[Cl:9])[cH:10][cH:11]1)([F:12])[F:13].[NH2:14][CH:15]1[CH2:16][N:17]([S:38](=[O:39])(=[O:40])[c:41]2[c:42]([Cl:48])[cH:43][c:44]([Cl:47])[cH:45][cH:46]2)[CH:18]2[N:19]([C:20]1=[O:21])[CH:22]([CH2:30][c:31]1[cH:32][cH:33][c:34]([Cl:37])[cH:35][cH:36]1)[C:23](=[O:29])[N:24]([CH:26]([CH3:27])[CH3:28])[CH2:25]2>>[F:1][C:2]([c:3]1[n:4][cH:5][c:6]([C:7](=[O:8])[NH:14][CH:15]2[CH2:16][N:17]([S:38](=[O:39])(=[O:40])[c:41]3[c:42]([Cl:48])[cH:43][c:44]([Cl:47])[cH:45][cH:46]3)[CH:18]3[N:19]([C:20]2=[O:21])[CH:22]([CH2:30][c:31]2[cH:32][cH:33][c:34]([Cl:37])[cH:35][cH:36]2)[C:23](=[O:29])[N:24]([CH:26]([CH3:27])[CH3:28])[CH2:25]3)[cH:10][cH:11]1)([F:12])[F:13]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-0853c052f17b4975b2920ba452257bcd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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