2-(2-Hydroxyethyl)pyridine → HCID 86683121, compound

HRID 920908Notes

Reaction equation

HRID 920908 reaction equation
[Br:1][C:2]1[C:10]2[C:9](=[O:11])[NH:8][N:7]=[CH:6][C:5]=2[S:4][CH:3]=1.[N:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[CH2:18][CH2:19]O>>[Br:1][C:2]1[C:10]2[C:9](=[O:11])[N:8]([CH2:19][CH2:18][C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][N:12]=3)[N:7]=[CH:6][C:5]=2[S:4][CH:3]=1

Participants

3

Reactant 2

HCID 76752-(2-Hydroxyethyl)pyridineHCID 86683120HCID 86683120, compound

Product 1

HCID 86683121HCID 86683121, compoundYield 76.3%

Procedure

The title compound was prepared in analogy to the process described in Example 3.4 starting from 3-bromo-5H-thieno[2,3-d]-pyridazin-4-one and 2-pyridin-2-yl-ethanol. Yield: 76.3%.

Sources & evidence

ORD record
ord-3e96cbe1ca8e4f7e861ad738e9687d71
Source dataset
uspto-grants-2016_03
Patent number
US09273068B2

Reaction notes

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